Cody Thomas passed for 133 yards and a touchdown and ran for 103 yards and a score for Oklahoma (7-3, 4-3 Big 12). Durron Neal had four catches for 57 yards and a touchdown, while K.J. Young added three receptions for 48 yards.

Patrick Mahomes was 27-of-50 for 393 yards and four touchdowns for Texas Tech (3-7, 1-6), which was eliminated from bowl eligibility. Devin Lauderdale had five catches for 83 yards and a score while Ian Sadler added four receptions for 89 yards and a touchdown.

Texas Tech got on the board first, with Mahomes finding Jakeem Grant on a 6-yard scoring pass to cap a 16-play, 87-yard drive that ate up 7:05 of the clock in the first quarter. The Sooners tied the game on Perine's 2-yard touchdown run with less than five minutes to play in the second quarter, but the Red Raiders responded less than two minutes later on Mahomes' 59-yard scoring hookup with Sadler for a 14-7 halftime lead.

Tech pushed the lead to 14 on Mahomes' 47-yard pass to Lauderdale early in the third, but Oklahoma tied the game by the end of the period thanks to Perine's 64-yard touchdown run and Thomas' 3-yard pass to Neal. Ryan Busin's 27-yard field goal put the Raiders on top in the first minute of the fourth, but the Sooners got touchdown runs from Thomas, Aaron Ripkowski and Perine in the last 10:06 to win going away.

GAME NOTEBOOK: Texas Tech RB DeAndre Washington came in averaging 88.4 rushing yards, second best in the Big 12, but was held to 56 yards on 12 carries. … Oklahoma finished with 384 rushing yards, moving to 20-0 under coach Bob Stoops when rushing for 300 or more yards. … The Sooners won their 11th straight road game against unranked Big 12 opponents.